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Treatment with the calcineurin inhibitor and immunosuppressant cyclosporine A impairs sensorimotor gating in Dark Agouti rats.

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第一作者： Jan,Brosda

第一单位： Institute of Pharmacology and Toxicology, School of Veterinary Medicine, Freie Universität Berlin, 14195, Berlin, Germany.

作者： Jan,Brosda ^[1] ; Thorsten,Becker ^[2] ; Mathis,Richter ^[3] ; Marie,Jakobs ^[3] ; Tina,Hörbelt ^[3] ; Ivo,Bendix ^[4] ; Laura,Lückemann ^[3] ; Manfred,Schedlowski ^[5] ; Martin,Hadamitzky ^[6]

作者单位： Institute of Pharmacology and Toxicology, School of Veterinary Medicine, Freie Universität Berlin, 14195, Berlin, Germany. ^[1] Institute of Biology, Department of Neurophysiology, Freie Universität Berlin, 14195, Berlin, Germany. ^[2] Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, 45122, Essen, Germany. ^[3] Department of Pediatrics I/Experimental perinatal Neuroscience, University Hospital Essen, University of Duisburg-Essen, 45122, Essen, Germany. ^[4] Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, 45122, Essen, Germany.;Department of Clinical Neuroscience, Osher Center for Integrative Medicine, Karolinska Institutet, 17177, Stockholm, Sweden. ^[5] Institute of Medical Psychology and Behavioral Immunobiology, University Hospital Essen, University of Duisburg-Essen, 45122, Essen, Germany. martin.hadamitzky@uk-essen.de. ^[6]

关键词 Calcineurin Cyclosporine A Drug side effects Prepulse inhibition Sensorimotor gating