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Attenuated CSF-1R signalling drives cerebrovascular pathology.

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第一作者： Conor,Delaney

第一单位： Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.

作者： Conor,Delaney ^[1] ; Michael,Farrell ^[2] ; Colin P,Doherty ^[3] ; Kiva,Brennan ^[4] ; Eoin,O'Keeffe ^[1] ; Chris,Greene ^[1] ; Kieva,Byrne ^[1] ; Eoin,Kelly ^[5] ; Niamh,Birmingham ^[6] ; Paula,Hickey ^[7] ; Simon,Cronin ^[6] ; Savvas N,Savvides ^[8] ; Sarah L,Doyle ^[4] ; Matthew,Campbell ^[9]

作者单位： Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland. ^[1] Department of Neuropathology, Beaumont Hospital, Dublin 9, Ireland. ^[2] Department of Neurology, Health Care Centre, St James's Hospital, Dublin 8, Ireland.;Academic Unit of Neurology, Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Ireland.;FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland. ^[3] Trinity College Institute of Neuroscience, Trinity College Dublin 2, Dublin 2, Ireland. ^[4] Department of Neurology, Health Care Centre, St James's Hospital, Dublin 8, Ireland. ^[5] Department of Medicine, University College Cork, Cork, Ireland. ^[6] Sligo Regional Hospital, Sligo, Ireland. ^[7] Unit for Structural Biology, Department of Biochemistry and Microbiology, Ghent University, Ghent, Belgium.;VIB-UGent Center for Inflammation Research, Ghent, Belgium. ^[8] Smurfit Institute of Genetics, Trinity College Dublin, Dublin 2, Ireland.;FutureNeuro SFI Research Centre, Royal College of Surgeons in Ireland, Dublin, Ireland. ^[9]

关键词 CSF-1 CSF-1R IL-34 adult-onset leucoencephalopathy with axonal spheroids and pigmented glia (ALSP)blood brain barrier