Cynaroside inhibits Leishmania donovani UDP-galactopyranose mutase and induces reactive oxygen species to exert antileishmanial response.

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作者： Shams,Tabrez ^[1] ; Fazlur,Rahman ^[1] ; Rahat,Ali ^[1] ; Abdulaziz S,Alouffi ^[2] ; Sajjadul Kadir,Akand ^[1] ; Bader Mohammed,Alshehri ^[3] ; Fahdah Ayed,Alshammari ^[4] ; Aftab,Alam ^[5] ; Mohammed A,Alaidarous ^[3] ; Saeed,Banawas ^[5] ; Abdul Aziz Bin,Dukhyil ^[3] ; Abdur,Rub ^[6]

作者单位： Infection and Immunity Lab (414), Department of Biotechnology, Jamia Millia Islamia (A Central University), New Delhi 110025, India. ^[1] King Abdulaziz City for Science and Technology, Riyadh, 11442, Saudi Arabia. ^[2] Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Al Majmaah 11952, Saudi Arabia. ^[3] College of Sciences and Literature Microbiology, Nothern Border University, KSA. ^[4] Centre for Interdisciplinary Research in Basic Sciences, Jamia Millia Islamia (A Central University), New Delhi 110025, India. ^[5] Health and Basic Sciences Research Center, Majmaah University, Al Majmaah, Saudi Arabia. ^[6] Department of Biomedical Sciences, Oregon State University, Corvallis, OR 97331, U.S.A. ^[7]

关键词 Cynaroside IC50 Leishmaniasis amastigote parasite promastigote