Evolution toward beta common chain receptor usage links the matrix proteins of HIV-1 and its ancestors to human erythropoietin.

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作者： Francesca,Caccuri ^[1] ; Pasqualina,D'Ursi ^[2] ; Matteo,Uggeri ^[2] ; Antonella,Bugatti ^[3] ; Pietro,Mazzuca ^[1] ; Alberto,Zani ^[1] ; Federica,Filippini ^[1] ; Mario,Salmona ^[1] ; Domenico,Ribatti ^[4] ; Mark,Slevin ^[5] ; Alessandro,Orro ^[6] ; Wuyuan,Lu ^[2] ; Pietro,Liò ^[7] ; Robert C,Gallo ^[8] ; Arnaldo,Caruso ^[9]

作者单位： Department of Molecular and Translational Medicine, University of Brescia Medical School, 25123 Brescia, Italy. ^[1] Institute of Technologies in Biomedicine, National Research Council, 20090 Segrate, Italy. ^[2] Department of Pharmacy, University of Genova, 16132 Genova, Italy. ^[3] Istituti di Ricovero e Cura a Carattere Assistenziale Istituto di Ricerche Farmacologiche Mario Negri, 20156 Milan, Italy. ^[4] Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, 70124 Bari, Italy. ^[5] School of Healthcare Science, Manchester Metropolitan University, M15GD Manchester, United Kingdom. ^[6] Institute of Human Virology, University of Maryland, Baltimore, MD 21201. ^[7] Department of Computer Science and Technology, University of Cambridge, CB3 0FD Cambridge, United Kingdom. ^[8] Institute of Human Virology, University of Maryland, Baltimore, MD 21201; rgallo@ihv.umaryland.edu arnaldo.caruso@unibs.it. ^[9] Department of Molecular and Translational Medicine, University of Brescia Medical School, 25123 Brescia, Italy; rgallo@ihv.umaryland.edu arnaldo.caruso@unibs.it. ^[10]

关键词 HIV-1 and HIV-2 ancestors HIV-1 evolutionary trajectory HIV-1 matrix protein p17 common beta chain receptor human erythropoietin