Direct derivation of the crystalline fraction of highly potent active pharmaceutical ingredients by X-ray powder diffraction.

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作者： Laura,Dall'Olio ^[1] ; Silvia,Spinozzi ^[2] ; Marco,Curzi ^[2] ; Enrico,Modena ^[2] ; Lucia,Maini ^[3]

作者单位： PolyCrystalLine SpA, Via della Cooperazione, 29, 40059 Medicina (BO), Italy; Dipartimento di Chimica "G. Ciamician", Università di Bologna, Via Selmi 2, 40126 Bologna, Italy. ^[1] PolyCrystalLine SpA, Via della Cooperazione, 29, 40059 Medicina (BO), Italy. ^[2] Dipartimento di Chimica "G. Ciamician", Università di Bologna, Via Selmi 2, 40126 Bologna, Italy. Electronic address: l.maini@unibo.it. ^[3]

关键词 Intensity–composition formula Kapton Powder X-ray diffraction crystallinity direct derivation

主题词粉末衍射(Powder Diffraction);粉剂(Powders);X线衍射(X-Ray Diffraction);X线(X-Rays)

DOI 10.1016/j.ejps.2020.105692

PMID 33373746

发布时间 2021-06-21

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