A Label-Free Cellular Proteomics Approach to Decipher the Antifungal Action of DiMIQ, a Potent Indolo[2,3-<i>b</i>]Quinoline Agent, against <i>Candida albicans</i> Biofilms.

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作者： Robert,Zarnowski ^[1] ; Anna,Jaromin ^[2] ; Agnieszka,Zagórska ^[3] ; Eddie G,Dominguez ^[4] ; Katarzyna,Sidoryk ^[1] ; Jerzy,Gubernator ^[2] ; David R,Andes ^[5]

作者单位： Department of Medicine, School of Medicine & Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA. ^[1] Department of Medical Microbiology, School of Medicine & Public Health, University of Wisconsin-Madison, Madison, WI 53706, USA. ^[2] Department of Lipids and Liposomes, Faculty of Biotechnology, University of Wroclaw, 50-383 Wroclaw, Poland. ^[3] Department of Medicinal Chemistry, Jagiellonian University Medical College, 30-688 Cracow, Poland. ^[4] Department of Pharmacy, Cosmetic Chemicals and Biotechnology, Team of Chemistry, Łukasiewicz Research Network-Industrial Chemistry Institute, 01-793 Warsaw, Poland. ^[5]

关键词 Candida DiMIQ antifungal biofilms indoloquinolines proteomics

主题词抗真菌药(Antifungal Agents);生物膜(Biofilms);白色念珠菌(Candida albicans);咔啉类(Carbolines);肿瘤蛋白质类(Neoplasm Proteins);蛋白质组学(Proteomics)

DOI 10.3390/ijms22010108

PMID 33374351

发布时间 2021-09-06

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