首页> Cancers> Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.

Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.

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第一作者： Michael,Hajek

第一单位： Department of Surgery, Otolaryngology, Yale University, New Haven, CT 06519-1369, USA.

作者： Michael,Hajek ^[1] ; Asel,Biktasova ^[1] ; Andrew,Sewell ^[1] ; Cyril,Gary ^[1] ; Paul,Cantalupo ^[2] ; Karen S,Anderson ^[3] ; Wendell G,Yarbrough ^[4] ; Natalia,Issaeva ^[4]

作者单位： Department of Surgery, Otolaryngology, Yale University, New Haven, CT 06519-1369, USA. ^[1] Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA. ^[2] Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06519-1369, USA.;Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, New Haven, CT 06519-1369, USA. ^[3] Department of Otolaryngology/Head and Neck Surgery, The University of North Carolina, Chapel Hill, NC 27599-7070, USA.;Department of Pathology and Lab Medicine, The University of North Carolina, Chapel Hill, NC 27599, USA.;Lineberger Comprehensive Cancer Center, The University of North Carolina, Chapel Hill, NC 27599, USA. ^[4]

关键词 DNA double strand breaks HPV demethylation head and neck cancer replication transcription

DOI 10.3390/cancers13010021

PMID 33374558

发布时间 2021-09-20

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