Macrophage LC3-associated phagocytosis is an immune defense against <i>Streptococcus pneumoniae</i> that diminishes with host aging.

导出 OA

翻译打印收藏纠错

作者： Megumi,Inomata ^[1] ; Shuying,Xu ^[2] ; Pallavi,Chandra ^[1] ; Simin N,Meydani ^[3] ; Genzou,Takemura ^[4] ; Jennifer A,Philips ^[5] ; John M,Leong ^[6]

作者单位： Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111. ^[1] Department of Oral Microbiology, Asahi University School of Dentistry, Mizuho, 501-0296 Gifu, Japan. ^[2] Graduate Program in Immunology, Tufts Graduate School of Biomedical Sciences, Boston, MA 02111. ^[3] Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, MO 63110. ^[4] Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110. ^[5] Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA 02111. ^[6] Department of Internal Medicine, Asahi University School of Dentistry, Mizuho, 501-0296 Gifu, Japan. ^[7] Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, MA 02111; john.leong@tufts.edu. ^[8]

关键词 LC3-associated phagocytosis Streptococcus pneumoniae aging autophagy bone-marrow-derived macrophages