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Stable isotope labeling derivatization combined with multiple-mass spectrometry technologies to monitor metabolites of tenuifoliside A incubated with intestinal bacteria incubation model.

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第一作者： Ningning,Zhao

第一单位： National Center of Mass Spectrometry in Changchun and Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China; Institute of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, 230029, China.

作者： Ningning,Zhao ^[1] ; Tiantian,Zhao ^[2] ; Meiling,Fan ^[3] ; Zhiqiang,Liu ^[4] ; Zifeng,Pi ^[2] ; Fengrui,Song ^[2] ; Junpeng,Xing ^[2] ; Shu,Liu ^[5]

作者单位： National Center of Mass Spectrometry in Changchun and Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China; Institute of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, 230029, China. ^[1] National Center of Mass Spectrometry in Changchun and Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China. ^[2] Key Laboratory of Medicinal Materials, Jilin Academy of Chinese Medicine Sciences, Changchun, 130021, China. ^[3] National Center of Mass Spectrometry in Changchun and Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China; Institute of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, 230029, China; State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China. ^[4] National Center of Mass Spectrometry in Changchun and Jilin Provincial Key Laboratory of Chinese Medicine Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, China. Electronic address: mslab20@ciac.ac.cn. ^[5]

关键词 Aromatic carboxylic acids monitoring Intestinal bacteria metabolism of tenuifoliside A Multiple-mass spectrometry technologies (MMS)Stable isotope labeling derivatization (SILD)

医学主题词细菌(Bacteria);二糖酶类(Disaccharidases);同位素标记(Isotope Labeling);串联质谱法(Tandem Mass Spectrometry)

DOI 10.1016/j.talanta.2020.121791

PMID 33379020

发布时间 2021-05-14

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准确一般字义偏差语意偏离译文作用小提交