Alkaloids of Zephyranthes citrina (Amaryllidaceae) and their implication to Alzheimer's disease: Isolation, structural elucidation and biological activity.

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作者： Eliška,Kohelová ^[1] ; Jana,Maříková ^[2] ; Jan,Korábečný ^[3] ; Daniela,Hulcová ^[4] ; Tomáš,Kučera ^[5] ; Daniel,Jun ^[3] ; Jakub,Chlebek ^[1] ; Jaroslav,Jenčo ^[1] ; Marcela,Šafratová ^[4] ; Martina,Hrabinová ^[3] ; Aneta,Ritomská ^[1] ; Milan,Malaník ^[6] ; Rozálie,Peřinová ^[1] ; Kateřina,Breiterová ^[1] ; Jiří,Kuneš ^[2] ; Lucie,Nováková ^[7] ; Lubomír,Opletal ^[1] ; Lucie,Cahlíková ^[8]

作者单位： ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic. ^[1] Department of Bioorganic and Organic Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic. ^[2] Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic. ^[3] ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic; Department of Pharmacognosy, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic. ^[4] Department of Toxicology and Military Pharmacy, Trebesska 1575, 500 05 Hradec Kralove, Czech Republic. ^[5] Department of Natural Drugs, Faculty of Pharmacy, Masaryk University, Palackého třída 1946/1, 61200 Brno, Czech Republic. ^[6] Department of Analytical Chemistry, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic. ^[7] ADINACO Research Group, Department of Pharmaceutical Botany, Faculty of Pharmacy, Charles University, Heyrovskeho 1203, 500 05 Hradec Kralove, Czech Republic. Electronic address: cahlikova@faf.cuni.cz. ^[8]

关键词 Alkaloids Alzheimer's disease Amaryllidaceae Docking studies Narcieliine Zephyranthes citrina