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Sequential fate-switches in stem-like cells drive the tumorigenic trajectory from human neural stem cells to malignant glioma.

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作者: Xiaofei,Wang [1] ; Ran,Zhou [2] ; Yanzhen,Xiong [1] ; Lingling,Zhou [3] ; Xiang,Yan [1] ; Manli,Wang [1] ; Fan,Li [4] ; Chuanxing,Xie [1] ; Yiming,Zhang [1] ; Zongyao,Huang [2] ; Chaoqiong,Ding [1] ; Kaidou,Shi [1] ; Weida,Li [4] ; Yu,Liu [5] ; Zhongwei,Cao [4] ; Zhen-Ning,Zhang [2] ; Shengtao,Zhou [5] ; Chong,Chen [2] ; Yan,Zhang [4] ; Lu,Chen [6] ; Yuan,Wang [7]
作者单位: Department of Neurology and Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and National Collaborative Innovation Center, Chengdu, Sichuan, 610041, China. [1] Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. [2] National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. [3] Department of Hematology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. [4] Institute of Regenerative Medicine, Shanghai East Hospital, Tongji University, Shanghai, 200092, China. [5] National Clinical Research Center for Geriatrics, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. yanzhang@scu.edu.cn. [6] Key Laboratory of Birth Defects and Related Diseases of Women and Children of MOE, State Key Laboratory of Biotherapy, West China Second Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. luchen@scu.edu.cn. [7] Department of Neurology and Department of Neurosurgery, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University and National Collaborative Innovation Center, Chengdu, Sichuan, 610041, China. wangyuan@scu.edu.cn. [8]
DOI 10.1038/s41422-020-00451-z
PMID 33390587
发布时间 2022-04-18
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