Development and evaluation of an ultrasound-triggered microbubble combined transarterial chemoembolization (TACE) formulation on rabbit VX2 liver cancer model.

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作者： Doyeon,Kim ^[1] ; Jae Hwan,Lee ^[2] ; Hyungwon,Moon ^[3] ; Minkyu,Seo ^[1] ; Hyounkoo,Han ^[1] ; Hongkeun,Yoo ^[1] ; Howon,Seo ^[4] ; Jingu,Lee ^[5] ; Sujung,Hong ^[4] ; Pilhan,Kim ^[5] ; Hak Jong,Lee ^[4] ; Jin Wook,Chung ^[5] ; Hyuncheol,Kim ^[4]

作者单位： Department of Chemical & Biomolecular Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Republic of Korea. ^[1] Department of Radiology, Seoul National University Bundang Hospital, 82, Gumi-ro 173beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Republic of Korea. ^[2] IMGT Co., Ltd., 172 Dolma-ro, Bundang-gu, Seongnam 13605, Republic of Korea. ^[3] Graduate School of Nanoscience and Technology, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Republic of Korea. ^[4] KI for Health Science and Technology (KIHST), Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. ^[5] Graduate School of Medical Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. ^[6] Department of Radiology, Seoul National University College of Medicine, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. ^[7] Institute of Radiation Medicine, Seoul National University Hospital, 101, Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea. ^[8] Department of Biomedical Engineering, Sogang University, 35 Baekbeom-ro, Mapo-gu, Seoul 04107, Republic of Korea. ^[9]

关键词 hepatocellular carcinoma nanomedicine sonoporation theranostics transarterial chemoembolization ultrasound microbubble