Generation of HBsAg DNA aptamer using modified cell-based SELEX strategy.

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作者： Mina,Mirian ^[1] ; Shirin,Kouhpayeh ^[2] ; Laleh,Shariati ^[3] ; Maryam,Boshtam ^[4] ; Ilnaz,Rahimmanesh ^[4] ; Leila,Darzi ^[5] ; Razieh,Taghizadeh ^[5] ; Ali,Jahanian-Najafabadi ^[5] ; Hossein,Khanahmad ^[1]

作者单位： Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Science, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. ^[1] Isfahan Neurosciences Research Center, Alzahra Research Institute, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. ^[2] Applied Physiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. ^[3] Department of Biomaterials, Nanotechnology and Tissue Engineering, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. ^[4] Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. ^[5] Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Islamic Republic of Iran. H_khanahmad@med.mui.ac.ir. ^[6]

关键词 Aptamer Hepatitis B surface antigen SELEX Single- stranded DNA