Virtual screening and repurposing of FDA-approved drugs from ZINC database to identify potential autophagy inhibitors exploiting autophagy related 4A cysteine peptidase as a target: potential as novel anti-cancer molecule.
第一作者:
Umesh
第一单位:
School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, India.
作者:
医学主题词
自噬(Autophagy);半胱氨酸(Cysteine);药物重新定位(Drug Repositioning);人类(Humans);分子动力学模拟(Molecular Dynamics Simulation);肿瘤(Neoplasms);肽水解酶类(Peptide Hydrolases);锌(Zinc)
DOI
10.1080/07391102.2020.1869100
PMID
33410378
发布时间
2022-08-29
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