DZ2002 alleviates psoriasis-like skin lesions via differentially regulating methylation of GATA3 and LCN2 promoters.
第一作者:
Li,Chen
第一单位:
Laboratory of Immunopharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Zhangjiang, Shanghai 201203, China; University of Chinese Academy of Sciences, NO.19A Yuquan Road, Beijing 100049, China.
作者:
医学主题词
腺嘌呤(Adenine);动物(Animals);消炎药(Anti-Inflammatory Agents);丁酸盐类(Butyrates);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);炎症趋化因子类(Chemokines);DNA甲基化(DNA Methylation);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);GATA3转录因子(GATA3 Transcription Factor);HL-60细胞(HL-60 Cells);人类(Humans);角蛋白细胞(Keratinocytes);小鼠, 近交BALB C(Mice, Inbred BALB C);中性白细胞浸润(Neutrophil Infiltration);启动区, 遗传(Promoter Regions, Genetic);银屑病(Psoriasis);皮肤(Skin);小鼠(Mice)
DOI
10.1016/j.intimp.2020.107334
PMID
33412493
发布时间
2024-02-26
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