Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.

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作者： Fayyaz,Ahamed ^[1] ; Mark,Van Criekinge ^[2] ; Zhen J,Wang ^[2] ; John,Kurhanewicz ^[2] ; Peder,Larson ^[2] ; Renuka,Sriram ^[2]

作者单位： University of California, Berkeley, Berkeley, California, USA. ^[1] Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, California, USA. ^[2]

关键词 aerobic glycolysis, cancer aggressiveness, dynamic nuclear polarization, hyperpolarized 13C magnetic resonance, lactate, lactate efflux, modeling, pyruvate, renal cell carcinoma

主题词藻酸盐(Alginates);动物(Animals);生物反应器(Bioreactors);癌, 肾细胞(Carcinoma, Renal Cell);细胞系, 肿瘤(Cell Line, Tumor);人类(Humans);肾肿瘤(Kidney Neoplasms);动力学(Kinetics);乳酸(Lactic Acid);小鼠(Mice);微球体(Microspheres);微技术(Microtechnology);模型, 动物(Models, Animal);模型, 生物学(Models, Biological);灌流(Perfusion);丙酮酸(Pyruvic Acid);信号处理, 计算机辅助(Signal Processing, Computer-Assisted)

DOI 10.1002/nbm.4467

PMID 33415771

发布时间 2021-11-11

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NMR in biomedicine

2021年34卷3期

e4467页

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Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.

NMR in biomedicine

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Modeling hyperpolarized lactate signal dynamics in cells, patient-derived tissue slice cultures and murine models.

NMR in biomedicine

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NMR in biomedicine

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