Evaluation of enzymatic activity of Babesia microti thioredoxin reductase (Bmi TrxR)-mutants and screening of its potential inhibitors.

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作者： Jinmiao,Lu ^[1] ; Nana,Wei ^[1] ; Jie,Cao ^[1] ; Yongzhi,Zhou ^[1] ; Haiyan,Gong ^[1] ; Houshuang,Zhang ^[2] ; Jinlin,Zhou ^[3]

作者单位： Key Laboratory of Animal Parasitology of Ministry of Agriculture, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China. ^[1] Key Laboratory of Animal Parasitology of Ministry of Agriculture, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China. Electronic address: zhanghoushuang@shvri.ac.cn. ^[2] Key Laboratory of Animal Parasitology of Ministry of Agriculture, Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai 200241, China. Electronic address: jinlinzhou@shvri.ac.cn. ^[3]

关键词 Babesia microti Enzyme activity Inhibitor TrxR mutation

主题词果氏贝斯虫(Babesia microti);突变(Mutation);硫氧还蛋白二硫化物还原酶(Thioredoxin-Disulfide Reductase)

DOI 10.1016/j.ttbdis.2020.101623

PMID 33418338

发布时间 2021-08-30

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