Potent DNA gyrase inhibitors bind asymmetrically to their target using symmetrical bifurcated halogen bonds.

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第一作者： Anja,Kolarič

第一单位： Theory Department, Laboratory for Cheminformatics, National Institute of Chemistry, Hajdrihova 19, 1001, Ljubljana, Slovenia.;Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia.

作者： Anja,Kolarič ^[1] ; Thomas,Germe ^[2] ; Martina,Hrast ^[3] ; Clare E M,Stevenson ^[2] ; David M,Lawson ^[2] ; Nicolas P,Burton ^[4] ; Judit,Vörös ^[2] ; Anthony,Maxwell ^[2] ; Nikola,Minovski ^[5] ; Marko,Anderluh ^[6]

作者单位： Theory Department, Laboratory for Cheminformatics, National Institute of Chemistry, Hajdrihova 19, 1001, Ljubljana, Slovenia.;Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia. ^[1] Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich, NR4 7UH, UK. ^[2] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia. ^[3] Inspiralis Ltd., Innovation Centre, Norwich Research Park, Colney Lane, Norwich, NR4 7GJ, UK. ^[4] Theory Department, Laboratory for Cheminformatics, National Institute of Chemistry, Hajdrihova 19, 1001, Ljubljana, Slovenia. nikola.minovski@ki.si. ^[5] Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Ljubljana, Aškerčeva 7, 1000, Ljubljana, Slovenia. marko.anderluh@ffa.uni-lj.si. ^[6]