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Strategic design and improvement of the internal electron transfer of heme b domain-fused glucose dehydrogenase for use in direct electron transfer-type glucose sensors.

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第一作者： Kohei,Ito

第一单位： Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan.

作者： Kohei,Ito ^[1] ; Junko,Okuda-Shimazaki ^[2] ; Katsuhiro,Kojima ^[3] ; Kazushige,Mori ^[3] ; Wakako,Tsugawa ^[1] ; Ryutaro,Asano ^[1] ; Kazunori,Ikebukuro ^[1] ; Koji,Sode ^[4]

作者单位： Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, 2-24-16 Naka-cho, Koganei, Tokyo, 184-8588, Japan. ^[1] Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC27599, USA. ^[2] Ultizyme International Ltd., 3-9-5 2F, Taihei, Sumida, Tokyo, 130-0011, Japan. ^[3] Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, NC27599, USA. Electronic address: ksode@email.unc.edu. ^[4]

关键词 Direct electron transfer Docking simulation Fusion protein Glucose dehydrogenase Surface electrostatics