首页> Journal of molecular biology> Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation.

Discriminative SKP2 Interactions with CDK-Cyclin Complexes Support a Cyclin A-Specific Role in p27KIP1 Degradation.

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第一作者： Marco,Salamina

第一单位： Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.

作者： Marco,Salamina ^[1] ; Bailey C,Montefiore ^[1] ; Mengxi,Liu ^[2] ; Daniel J,Wood ^[1] ; Richard,Heath ^[1] ; James R,Ault ^[3] ; Lan-Zhen,Wang ^[1] ; Svitlana,Korolchuk ^[1] ; Arnaud,Baslé ^[4] ; Martyna W,Pastok ^[1] ; Judith,Reeks ^[1] ; Natalie J,Tatum ^[1] ; Frank,Sobott ^[3] ; Stefan T,Arold ^[5] ; Michele,Pagano ^[2] ; Martin E M,Noble ^[1] ; Jane A,Endicott ^[6]

作者单位： Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. ^[1] Department of Biochemistry and Molecular Pharmacology, Perlmutter NYU Cancer Center, New York University Grossman School of Medicine, and Howard Hughes Medical Institute, The Alexandria Center of Life Science, East Tower, 450 E, 29th Street, New York, NY 10016, USA. ^[2] Astbury Centre for Structural Molecular Biology, School of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, UK. ^[3] Biosciences Institute, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. ^[4] Division of Biological and Environmental Sciences and Engineering (BESE), Computational Bioscience Research Center (CBRC), King Abdullah University of Science and Technology (KAUST), Thuwal 23955-6900, Saudi Arabia; Centre de Biochimie Structurale, CNRS, INSERM, Université de Montpellier, 34090 Montpellier, France. ^[5] Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Newcastle University, Paul O'Gorman Building, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. Electronic address: jane.endicott@ncl.ac.uk. ^[6]

关键词 cell cycle checkpoint protein kinase signaling ubiquitination