Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: Potential role of mTORC1-S6K1.

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作者： Nadia,Di Pietrantonio ^[1] ; Carola,Palmerini ^[1] ; Caterina,Pipino ^[1] ; Maria Pompea Antonia,Baldassarre ^[2] ; Giuseppina,Bologna ^[2] ; Angelika,Mohn ^[3] ; Cosimo,Giannini ^[4] ; Paola,Lanuti ^[2] ; Francesco,Chiarelli ^[4] ; Assunta,Pandolfi ^[1] ; Natalia,Di Pietro ^[5]

作者单位： Department of Medical, Oral and Biotechnological Sciences, Italy; Center for Advanced Studies and Technology - CAST (ex CeSI-MeT), University G. d'Annunzio of Chieti-Pescara, Italy. ^[1] Department of Medicine and Aging Sciences, Italy; Center for Advanced Studies and Technology - CAST (ex CeSI-MeT), University G. d'Annunzio of Chieti-Pescara, Italy. ^[2] Pediatrics Division, Hospital SS. Annunziata, Chieti, Italy. ^[3] Department of Medicine and Aging Sciences, Italy; Pediatrics Division, Hospital SS. Annunziata, Chieti, Italy. ^[4] Department of Medical, Oral and Biotechnological Sciences, Italy; Center for Advanced Studies and Technology - CAST (ex CeSI-MeT), University G. d'Annunzio of Chieti-Pescara, Italy. Electronic address: n.dipietro@unich.it. ^[5]

关键词 Childhood obesity Endothelial dysfunction Insulin resistance Monocytes adhesion Oxidative stress Rapamycin

主题词细胞黏附(Cell Adhesion);细胞, 培养的(Cells, Cultured);儿童(Child);内皮细胞(Endothelial Cells);人类(Humans);胰岛素(Insulin);单核细胞(Monocytes);肥胖症(Obesity);血浆(Plasma);核糖体蛋白质S6激酶类, 70-kDa(Ribosomal Protein S6 Kinases, 70-kDa);信号传导(Signal Transduction)

DOI 10.1016/j.bbadis.2021.166076

PMID 33422633

发布时间 2021-07-02

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Biochimica et biophysica acta. Molecular basis of disease

2021年1867卷4期

166076页

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Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: Potential role of mTORC1-S6K1.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

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Plasma from obese children increases monocyte-endothelial adhesion and affects intracellular insulin signaling in cultured endothelial cells: Potential role of mTORC1-S6K1.

Biochimica et biophysica acta. Molecular basis of disease

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Biochimica et biophysica acta. Molecular basis of disease

相关期刊

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