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Responses of oral-microflora-exposed dental pulp to capping with a triple antibiotic paste or calcium hydroxide cement in mouse molars.

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作者单位: Division of Anatomy and Cell Biology of the Hard Tissue, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, 2-5274 Gakkocho-dori, Chuo-ku, Niigata, 951-8514, Japan. [1] School of Stomatology, Faculty of Health Science, Universidad Cientifica del Sur, Av. Paseo de la República 5544, Miraflores, 15074, Lima, Peru. [2] Division of Clinical Chemistry, Department of Medical Technology, Niigata University Graduate School of Health Sciences, 2-746 Asahimachi-dori, Chuo-ku, Niigata, 951-8518, Japan. [3] Division of Pediatric Dentistry, Department of Oral Health Science, Niigata University Graduate School of Medical and Dental Sciences, 2-5274 Gakkocho-dori, Chuo-ku, Niigata, 951-8514, Japan. [4] Niigata City Dental Health and Welfare Center, 3-3-11 Shichikuyama, Chuo-ku, Niigata, 950-0914, Japan. [5]
关键词 ANOVA, One-way analysis of varianceAZAN, Azocarmine and aniline blueAnti-bacterial agentsBMPs, Bone morphogenetic proteinsBirc5, Baculoviral IAP Repeat Containing 5CH, Calcium hydroxideCell differentiationCell proliferationCt, Cycle thresholdDAP, Double antibiotic pasteDCs, Dendritic cellsDNA, Deoxyribonucleic acidDPC, Direct pulp cappingDPSCs, Dental pulp stem cellsDental cavity preparationDental pulpFGFs, Fibroblast growth factorsGM-CSF, Granulocyte-macrophage colony-stimulating factorH2O2, Hydrogen peroxideHE, Hematoxylin-eosinHLA-DR-immunopositive cells, Human Leukocyte Antigen – DR isotype-immunopositive cellsM, MacrogolMHC, Major histocompatibility complexMP, Macrogol (M) mixed with propylene glycol (P)MSCs, Mesenchymal stem cellsMTA, Mineral trioxide aggregateMice (crlj:CD1)Oct 3/4 A, Octamer binding transcription factor 3/4 AOct 3/4?B, Octamer binding transcription factor 3/4?BP, Propylene glycolPBS, Phosphate-buffered salinePcna, Proliferating cell nuclear antigenREP, Regenerative endodontic proceduresRNA, Ribonucleic acidRT, Reverse transcriptionSCAP, Stem cells of the apical papillaSox 10, SRY-related HMG-box 10TAC, Triple antibiotic combination (a mixture of metronidazole, ciprofloxacin, and minocycline)TAC-P, Triple antibiotic combination and propylene glycolTAP, Triple antibiotic pasteTAS, Triple antibiotic solutionTGFβ, Transforming growth factor βTUNEL assay, Terminal deoxynucleotidyl transferase dUTP nick end labeling assayTris–HCl buffer, Tris (hydroxymethyl) aminomethane (THAM) hydrochloride bufferYap1, Yes-associated protein 1cDNA, Complementary deoxyribonucleic acidmRNA, Messenger ribonucleic acidmTAP, Modified triple antibiotic pasteqRT-PCR, Quantitative real-time polymerase chain reactionαTCP, Alpha tricalcium phosphateβ-actin, Beta-actin
DOI 10.1016/j.reth.2020.10.001
PMID 33426222
发布时间 2022-04-19
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Regenerative therapy

2020年15卷

216-225页

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