Cholesterol synthesis inhibition promotes axonal regeneration in the injured central nervous system.-论文-万方医学网

作者： Alireza P,Shabanzadeh ^[1] ; Jason,Charish ^[2] ; Nardos G,Tassew ^[3] ; Nahal,Farhani ^[4] ; Jinzhou,Feng ^[5] ; Xinjue,Qin ^[5] ; Shuzo,Sugita ^[4] ; Andrea J,Mothe ^[4] ; Thomas,Wälchli ^[4] ; Paulo D,Koeberle ^[6] ; Philippe P,Monnier ^[7]

作者单位： Krembil Research Institute, KDT 8-417, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada; Department of Physiology, Donald K. Johnson Research Institute, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada; Department of Anatomy, Faculty of Medicine, University of Toronto, Toronto M5S 1A8, Ontario, Canada. ^[1] Krembil Research Institute, KDT 8-417, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto M5S 1A8, Ontario, Canada. ^[2] Krembil Research Institute, KDT 8-417, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada; Department of Physiology, Donald K. Johnson Research Institute, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada. ^[3] Krembil Research Institute, KDT 8-417, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada. ^[4] Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400016, China. ^[5] Department of Anatomy, Faculty of Medicine, University of Toronto, Toronto M5S 1A8, Ontario, Canada. ^[6] Krembil Research Institute, KDT 8-417, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada; Department of Physiology, Donald K. Johnson Research Institute, 60 Leonard St., Toronto M5T 2S8, Ontario, Canada; Department of Ophthalmology, Faculty of Medicine, University of Toronto, Toronto M5S 1A8, Ontario, Canada; Department of Physiology, Faculty of Medicine, University of Toronto, Toronto M5S 1A8, Ontario, Canada. Electronic address: philippe.monnier@uhnresearch.ca. ^[7]

主题词动物(Animals);抗胆固醇血症药(Anticholesteremic Agents);轴突(Axons);细胞存活(Cell Survival);鸡胚(Chick Embryo);羟甲基戊二酰基CoA还原酶抑制剂(Hydroxymethylglutaryl-CoA Reductase Inhibitors);洛伐他汀(Lovastatin);膜微区(Membrane Microdomains);膜蛋白质类(Membrane Proteins);髓鞘(Myelin Sheath);神经再生(Nerve Regeneration);神经元(Neurons);视神经(Optic Nerve);视神经损伤(Optic Nerve Injuries);光感受器细胞(Photoreceptor Cells);异戊烯化(Prenylation);药物前体(Prodrugs);大鼠(Rats);视网膜(Retina);色素性视网膜炎(Retinitis Pigmentosa);反式-1,4-二(2-氯苯甲酰胺甲基)环己烷二氢氯化物(trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride)

DOI 10.1016/j.nbd.2021.105259

PMID 33434618

发布时间 2021-12-30

检索历史清除

Cholesterol synthesis inhibition promotes axonal regeneration in the injured central nervous system.

Neurobiology of disease

相似文献

Neurobiology of disease

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Cholesterol synthesis inhibition promotes axonal regeneration in the injured central nervous system.

Neurobiology of disease

相似文献

Neurobiology of disease

相关期刊

检索历史清除