Tumor microenvironment-responsive PEGylated heparin-pyropheophorbide-a nanoconjugates for photodynamic therapy.-论文-万方医学网

第一作者： Yahui,Wu

第一单位： Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China.

作者： Yahui,Wu ^[1] ; Fangnian,Li ^[2] ; Xiaoqin,Zhang ^[3] ; Zhiqian,Li ^[1] ; Qianfeng,Zhang ^[1] ; Wenjia,Wang ^[1] ; Dayi,Pan ^[1] ; Xiuli,Zheng ^[1] ; Zhongwei,Gu ^[1] ; Hu,Zhang ^[4] ; Qiyong,Gong ^[5] ; Kui,Luo ^[6]

作者单位： Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China. ^[1] Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China; Kindos Pharmaceutical Co., Ltd., No. 8-9 Kexin Road, Chengdu Hi-Tech Comprehensive Bonded Zone, Chengdu, 611731, China. ^[2] Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China; College of Preclinical Medicine, Southwest Medical University, Luzhou, 646000, China. ^[3] Amgen Bioprocessing Centre, Keck Graduate Institute, CA, 91711, USA. ^[4] Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China; Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu, 610041, China. ^[5] Huaxi MR Research Center (HMRRC), Department of Radiology, West China Hospital, Functional and Molecular Imaging Key Laboratory of Sichuan Province, Sichuan University, Chengdu, 610041, China. Electronic address: luokui@scu.edu.cn. ^[6]

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞凋亡(Apoptosis);细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);叶绿素(Chlorophyll);女(雌)性(Female);肝素(Heparin);激光(Lasers);光(Light);乳房肿瘤, 实验性(Mammary Neoplasms, Experimental);小鼠(Mice);小鼠, 近交BALB C(Mice, Inbred BALB C);纳米共轭体(Nanoconjugates);光化学疗法(Photochemotherapy);光敏感药(Photosensitizing Agents);聚乙烯二醇类(Polyethylene Glycols);活性氧(Reactive Oxygen Species);球形体, 细胞(Spheroids, Cellular);治疗结果(Treatment Outcome);肿瘤负荷(Tumor Burden);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.carbpol.2020.117490

PMID 33436250

发布时间 2021-04-08

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Tumor microenvironment-responsive PEGylated heparin-pyropheophorbide-a nanoconjugates for photodynamic therapy.

Carbohydrate polymers

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Carbohydrate polymers

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Tumor microenvironment-responsive PEGylated heparin-pyropheophorbide-a nanoconjugates for photodynamic therapy.

Carbohydrate polymers

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Carbohydrate polymers

相关期刊

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