FUS and TDP-43 Phases in Health and Disease.

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第一作者： Bede,Portz

第一单位： Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

作者： Bede,Portz ^[1] ; Bo Lim,Lee ^[1] ; James,Shorter ^[2]

作者单位： Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. ^[1] Department of Biochemistry and Biophysics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: jshorter@pennmedicine.upenn.edu. ^[2]

关键词 aggregation neurodegenerative diseases phase separation prion-like domains: RNA-binding proteins stress granules

主题词肌萎缩侧索硬化(Amyotrophic Lateral Sclerosis);DNA结合蛋白质类(DNA-Binding Proteins);额颞叶痴呆(Frontotemporal Dementia);人类(Humans);神经变性疾病(Neurodegenerative Diseases);RNA结合蛋白质FUS(RNA-Binding Protein FUS)

DOI 10.1016/j.tibs.2020.12.005

PMID 33446423

发布时间 2024-04-02

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