Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination.-论文-万方医学网

作者： Kyosuke,Nakamura ^[1] ; Georg,Kustatscher ^[2] ; Constance,Alabert ^[3] ; Martina,Hödl ^[3] ; Ignasi,Forne ^[4] ; Moritz,Völker-Albert ^[4] ; Shankha,Satpathy ^[5] ; Tracey E,Beyer ^[1] ; Niels,Mailand ^[5] ; Chunaram,Choudhary ^[5] ; Axel,Imhof ^[4] ; Juri,Rappsilber ^[6] ; Anja,Groth ^[7]

作者单位： The Novo Nordisk Center for Protein Research (CPR), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. ^[1] Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK. ^[2] Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. ^[3] Biomedical Center, Chromatin Proteomics Group, Department of Molecular Biology, Faculty of Medicine, Ludwig-Maximilians-Universität München, Großhaderner Strasse 9, 82152 Planegg- Martinsried, Germany. ^[4] The Novo Nordisk Center for Protein Research (CPR), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. ^[5] Wellcome Centre for Cell Biology, University of Edinburgh, Edinburgh EH9 3BF, UK; Bioanalytics, Institute of Biotechnology, Technische Universität Berlin, 13355 Berlin, Germany. Electronic address: juri.rappsilber@tu-berlin.de. ^[6] The Novo Nordisk Center for Protein Research (CPR), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark; Biotech Research and Innovation Centre (BRIC), Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark. Electronic address: anja.groth@cpr.ku.dk. ^[7]

主题词 BRCA1蛋白质(BRCA1 Protein);喜树碱(Camptothecin);细胞周期蛋白质类(Cell Cycle Proteins);细胞系, 肿瘤(Cell Line, Tumor);染色质(Chromatin);DNA(DNA);DNA断裂, 双链(DNA Breaks, Double-Stranded);DNA复制(DNA Replication);DNA拓扑异构酶类, Ⅰ型(DNA Topoisomerases, Type I);成纤维细胞(Fibroblasts);基因表达调控(Gene Expression Regulation);人类(Humans);蛋白质结合(Protein Binding);蛋白质组学(Proteomics);原癌基因蛋白质类(Proto-Oncogene Proteins);吡啶类(Pyridines);喹啉类(Quinolines);RNA, 小分子干扰(RNA, Small Interfering);信号传导(Signal Transduction);拓扑异构酶I抑制剂(Topoisomerase I Inhibitors);泛素蛋白连接酶类(Ubiquitin-Protein Ligases);泛素化(Ubiquitination)

DOI 10.1016/j.molcel.2020.12.025

PMID 33450211

发布时间 2023-12-13

检索历史清除

Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination.

Molecular cell

相似文献

Molecular cell

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Proteome dynamics at broken replication forks reveal a distinct ATM-directed repair response suppressing DNA double-strand break ubiquitination.

Molecular cell

相似文献

Molecular cell

相关期刊

检索历史清除