Dynamic Processing of a Common Oxidative DNA Lesion by the First Two Enzymes of the Base Excision Repair Pathway.
第一作者:
Austin T,Raper
第一单位:
The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210, USA.
作者:
主题词
结合部位(Binding Sites);DNA(DNA);DNA损伤(DNA Damage);DNA糖基化酶类(DNA Glycosylases);DNA修复(DNA Repair);DNA-(无嘌呤或无嘧啶位点)裂合酶(DNA-(Apurinic or Apyrimidinic Site) Lyase);荧光共振能量转移(Fluorescence Resonance Energy Transfer);基因表达(Gene Expression);基因组, 人(Genome, Human);基因组不稳定性(Genomic Instability);人类(Humans);动力学(Kinetics);模型, 分子(Models, Molecular);突变(Mutation);核酸构象(Nucleic Acid Conformation);氧化还原(Oxidation-Reduction);蛋白质结合(Protein Binding);蛋白质相互作用域和基序(Protein Interaction Domains and Motifs);底物特异性(Substrate Specificity)
DOI
10.1016/j.jmb.2021.166811
PMID
33450252
发布时间
2022-03-06
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