N-myc downstream-regulated gene 2 promotes the protein stability of estrogen receptor beta via inhibition of ubiquitin-protein ligase E3A to suppress colorectal cancer.

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作者： Jun,Zhu ^[1] ; Yongzhi,Lv ^[2] ; Jun,Hao ^[3] ; Tingyu,Shi ^[4] ; Shuai,Wang ^[1] ; Ke,Wang ^[1] ; Xiaoyan,Fan ^[3] ; Yuan,Guo ^[5] ; Jian,Zhang ^[6] ; Jipeng,Li ^[1]

作者单位： State Key Laboratory of Cancer Biology, Institute of Digestive Diseases, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. ^[1] The First Affiliated Hospital of Xi'an Medical University, Xi'an, China. ^[2] Department of Experiment Surgery, Xijing Hospital, The Fourth Military Medical University, Xi'an, China. ^[3] Department of Basic Medicine, The Fourth Military Medical University, Xi'an, China. ^[4] School of Clinical Medicine, Xi'an Medical University, Xi'an, China. ^[5] State Key Laboratory of Cancer Biology, Department of Biochemistry and Molecular Biology, The Fourth Military Medical University, Xi'an, China. ^[6]

关键词 Colorectal cancer (CRC)ERβ NDRG2 UBE3A ubiquitination degradation

DOI 10.21037/jgo-20-557

PMID 33456993

发布时间 2022-04-19

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