Kdm2a deficiency in macrophages enhances thermogenesis to protect mice against HFD-induced obesity by enhancing H3K36me2 at the Pparg locus.

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第一作者： Longmin,Chen

第一单位： The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

作者： Longmin,Chen ^[1] ; Jing,Zhang ^[1] ; Yuan,Zou ^[1] ; Faxi,Wang ^[1] ; Jingyi,Li ^[1] ; Fei,Sun ^[1] ; Xi,Luo ^[1] ; Meng,Zhang ^[1] ; Yanchao,Guo ^[2] ; Qilin,Yu ^[1] ; Ping,Yang ^[2] ; Qing,Zhou ^[1] ; Zhishui,Chen ^[1] ; Huilan,Zhang ^[1] ; Quan,Gong ^[1] ; Jiajun,Zhao ^[3] ; Decio L,Eizirik ^[1] ; Zhiguang,Zhou ^[4] ; Fei,Xiong ^[5] ; Shu,Zhang ^[6] ; Cong-Yi,Wang ^[7]

作者单位： The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. ^[1] Department of Nephrology,Tongji Hospital, Tongji College of Medicine, Huazhong University of Science and Technology, Wuhan, China. ^[2] Key Laboratory of Organ Transplantation, Ministry of Education, NHC Key Laboratory of Organ Transplantation, Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Tongji Hospital, Wuhan, China. ^[3] Clinical Molecular Immunology Center, Department of Immunology, School of Medicine, Yangtze University, Jingzhou, China. ^[4] Department of Endocrinology and Metabolism, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, China. ^[5] ULB Center for Diabetes Research, Université Libre de Bruxelles, 808 Route de Lennik, B-1070, Brussels, Belgium. ^[6] Diabetes Center, The Second Xiangya Hospital, Institute of Metabolism and Endocrinology, Central South University, Changsha, China. ^[7] The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. feixiong@tjh.tjmu.edu.cn. ^[8] The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. szhang@tjh.tjmu.edu.cn. ^[9] The Center for Biomedical Research, Department of Respiratory and Critical Care Medicine, NHC Key Laboratory of Respiratory Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China. wangcy@tjh.tjmu.edu.cn. ^[10]