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Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles.

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第一作者: Diogo Henrique,Kita
第一单位: Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.;Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
作者单位: Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.;Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. [1] EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France. [2] Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. [3] Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil.;Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. [4] Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. [5] Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. [6] Laboratory of Applied Organic Chemistry, Synthesis of Biomolecules and Molecular Modelling Group, Badji-Mokhtar-Annaba University, Box 12, 23000, Annaba, Algeria. [7] Département Sciences de la Matière, Faculté des Sciences exactes et Sciences de la nature et de la vie, Université Larbi Ben M'hidi, Oum El Bouaghi, Algeria.;Research Unit for Chemistry of the Environment and Molecular Structural, University of Constantine 1, Constantine, Algeria. [8] EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France.;Small Molecules for Biological Targets Team, Centre de recherche en cancérologie de Lyon, Centre Léon Bérard, CNRS 5286, INSERM 1052, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France. [9] Institut für Pharmazeutische und Medizinische Chemie, PharmaCampus, Westfälische Wilhelms-Universität Münster, Corrensstr. 48, 48149, Münster, Germany. [10] Department of Physics, Federal Technological University of Paraná, Curitiba, PR, 80230-901, Brazil. [11] Pharmaceutical Sciences Graduate Program, Laboratory of Cancer Drug Resistance, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. gvaldameri@ufpr.br.;Department of Clinical Analysis, Federal University of Parana, Curitiba, PR, 80210-170, Brazil. gvaldameri@ufpr.br. [12] EA 4446 Bioactive Molecules and Medicinal Chemistry, Faculté de Pharmacie - ISPB, SFR Santé Lyon-Est CNRS UMS3453 - INSERM US7, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France. marc.le-borgne@univ-lyon1.fr.;Small Molecules for Biological Targets Team, Centre de recherche en cancérologie de Lyon, Centre Léon Bérard, CNRS 5286, INSERM 1052, Université Claude Bernard Lyon 1, Univ Lyon, 69373, Lyon, France. marc.le-borgne@univ-lyon1.fr. [13]
DOI 10.1038/s41598-020-79892-w
PMID 33469044
发布时间 2021-10-06
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