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Single-cell lineages reveal the rates, routes, and drivers of metastasis in cancer xenografts.

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第一作者： Jeffrey J,Quinn

第一单位： Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.;Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.;Inscripta, Inc., Boulder, CO, USA.

作者： Jeffrey J,Quinn ^[1] ; Matthew G,Jones ^[2] ; Ross A,Okimoto ^[3] ; Shigeki,Nanjo ^[3] ; Michelle M,Chan ^[4] ; Nir,Yosef ^[5] ; Trever G,Bivona ^[6] ; Jonathan S,Weissman ^[7]

作者单位： Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.;Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.;Inscripta, Inc., Boulder, CO, USA. ^[1] Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.;Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.;Biological and Medical Informatics Graduate Program, University of California, San Francisco, San Francisco, CA, USA.;Integrative Program in Quantitative Biology, University of California, San Francisco, San Francisco, CA, USA.;Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. ^[2] UCSF Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.;Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. ^[3] Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA.;Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.;Department of Molecular Biology, Princeton University, Princeton, NJ, USA. ^[4] Center for Computational Biology, University of California, Berkeley, Berkeley, CA, USA. weissman@wi.mit.edu trever.bivona@ucsf.edu niryosef@berkeley.edu.;Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA, USA.;Chan Zuckerberg Biohub Investigator, San Francisco, CA, USA.;Ragon Institute of Massachusetts General Hospital, MIT and Harvard University, Cambridge, MA, USA. ^[5] Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. weissman@wi.mit.edu trever.bivona@ucsf.edu niryosef@berkeley.edu.;UCSF Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.;Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, USA. ^[6] Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA, USA. weissman@wi.mit.edu trever.bivona@ucsf.edu niryosef@berkeley.edu.;Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA, USA.;Whitehead Institute, Cambridge, MA, USA.;Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA. ^[7]