换一批
第一作者：
Christian,Koelsche
第一单位：
Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of General Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
作者：
Christian,Koelsche [1]
;
Daniel,Schrimpf [2]
;
Damian,Stichel [3]
;
Martin,Sill [4]
;
Felix,Sahm [2]
;
David E,Reuss [2]
;
Mirjam,Blattner [5]
;
Barbara,Worst [6]
;
Christoph E,Heilig [7]
;
Katja,Beck [8]
;
Peter,Horak [7]
;
Simon,Kreutzfeldt [7]
;
Elke,Paff [6]
;
Sebastian,Stark [6]
;
Pascal,Johann [6]
;
Florian,Selt [9]
;
Jonas,Ecker [9]
;
Dominik,Sturm [6]
;
Kristian W,Pajtler [10]
;
Annekathrin,Reinhardt [2]
;
Annika K,Wefers [2]
;
Philipp,Sievers [2]
;
Azadeh,Ebrahimi [3]
;
Abigail,Suwala [2]
;
Francisco,Fernández-Klett [2]
;
Belén,Casalini [3]
;
Andrey,Korshunov [2]
;
Volker,Hovestadt [11]
;
Felix K F,Kommoss [12]
;
Mark,Kriegsmann [12]
;
Matthias,Schick [13]
;
Melanie,Bewerunge-Hudler [13]
;
Till,Milde [9]
;
Olaf,Witt [9]
;
Andreas E,Kulozik [14]
;
Marcel,Kool [4]
;
Laura,Romero-Pérez [15]
;
Thomas G P,Grünewald [15]
;
Thomas,Kirchner [16]
;
Wolfgang,Wick [17]
;
Michael,Platten [18]
;
Andreas,Unterberg [19]
;
Matthias,Uhl [20]
;
Amir,Abdollahi [21]
;
Jürgen,Debus [21]
;
Burkhard,Lehner [22]
;
Christian,Thomas [23]
;
Martin,Hasselblatt [23]
;
Werner,Paulus [23]
;
Christian,Hartmann [24]
;
Ori,Staszewski [25]
;
Marco,Prinz [26]
;
Jürgen,Hench [27]
;
Stephan,Frank [27]
;
Yvonne M H,Versleijen-Jonkers [28]
;
Marije E,Weidema [28]
;
Thomas,Mentzel [29]
;
Klaus,Griewank [30]
;
Enrique,de Álava [31]
;
Juan Díaz,Martín [32]
;
Miguel A Idoate,Gastearena [33]
;
Kenneth Tou-En,Chang [34]
;
Sharon Yin Yee,Low [35]
;
Adrian,Cuevas-Bourdier [36]
;
Michel,Mittelbronn [37]
;
Martin,Mynarek [38]
;
Stefan,Rutkowski [38]
;
Ulrich,Schüller [39]
;
Viktor F,Mautner [40]
;
Jens,Schittenhelm [41]
;
Jonathan,Serrano [42]
;
Matija,Snuderl [42]
;
Reinhard,Büttner [43]
;
Thomas,Klingebiel [44]
;
Rolf,Buslei [45]
;
Manfred,Gessler [46]
;
Pieter,Wesseling [47]
;
Winand N M,Dinjens [48]
;
Sebastian,Brandner [49]
;
Zane,Jaunmuktane [50]
;
Iben,Lyskjær [51]
;
Peter,Schirmacher [12]
;
Albrecht,Stenzinger [12]
;
Benedikt,Brors [52]
;
Hanno,Glimm [53]
;
Christoph,Heining [54]
;
Oscar M,Tirado [55]
;
Miguel,Sáinz-Jaspeado [55]
;
Jaume,Mora [56]
;
Javier,Alonso [57]
;
Xavier Garcia,Del Muro [58]
;
Sebastian,Moran [59]
;
Manel,Esteller [60]
;
Jamal K,Benhamida [61]
;
Marc,Ladanyi [61]
;
Eva,Wardelmann [62]
;
Cristina,Antonescu [61]
;
Adrienne,Flanagan [63]
;
Uta,Dirksen [64]
;
Peter,Hohenberger [65]
;
Daniel,Baumhoer [66]
;
Wolfgang,Hartmann [67]
;
Christian,Vokuhl [68]
;
Uta,Flucke [69]
;
Iver,Petersen [70]
;
Gunhild,Mechtersheimer [12]
;
David,Capper [71]
;
David T W,Jones [5]
;
Stefan,Fröhling [7]
;
Stefan M,Pfister [10]
;
Andreas,von Deimling [72]
作者单位：
Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of General Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
[1]
Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[2]
Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[3]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[4]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Pediatric Glioma Research Group, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[5]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Pediatric Glioma Research Group, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
[6]
Division of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.
[7]
Division of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Heidelberg and German Cancer Research Center (DKFZ), German Cancer Consortium (DKTK), Heidelberg, Germany.;Heidelberg Center for Personalized Oncology (HIPO), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[8]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.;Clinical Cooperation Unit Pediatric Oncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[9]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Division of Pediatric Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
[10]
Broad Institute of MIT and Harvard, Cambridge, MA, USA.;Department of Pathology and Center for Cancer Research, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
[11]
Department of General Pathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany.
[12]
Genomics and Proteomics Core Facility, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[13]
Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany.;Department of Pediatric Oncology, Hematology and Immunology, Heidelberg University Hospital, Heidelberg, Germany.
[14]
Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
[15]
Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
[16]
Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.;Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[17]
Department of Neurology, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany.;Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[18]
Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
[19]
Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.;Heidelberg Institute of Radiation Oncology (HIRO), National Center for Radiation Research in Oncology (NCRO), Heidelberg, Germany.
[20]
Department of Radiation Oncology, Heidelberg University Hospital, Heidelberg, Germany.;Heidelberg Institute of Radiation Oncology (HIRO), National Center for Radiation Research in Oncology (NCRO), Heidelberg, Germany.;Heidelberg Ion-Beam Therapy Center (HIT), Heidelberg, Germany.;Translational Radiation Oncology, German Cancer Consortium (DKTK), National Center for Tumor Diseases (NCT), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[21]
Department of Orthopaedics, Trauma Surgery and Paraplegiology, Heidelberg University Hospital, Heidelberg, Germany.
[22]
Institute of Neuropathology, University Hospital Münster, Münster, Germany.
[23]
Department of Neuropathology, Institute of Pathology, Hannover Medical School (MHH), Hannover, Germany.
[24]
Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.;Berta-Ottenstein-Programme for Clinician Scientists, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
[25]
Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.;Signalling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.;Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, Freiburg, Germany.
[26]
Department of Neuropathology, Institute of Pathology, Basel University Hospital, Basel, Switzerland.
[27]
Department of Medical Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
[28]
Dermatopathology Bodensee, Friedrichshafen, Germany.
[29]
Department of Dermatology, University Hospital Essen, West German Cancer Center, University Duisburg-Essen, Essen, Germany.
[30]
Department of Pathology, Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital, CSIC/University of Sevilla/CIBERONC, Seville, Spain.;Department of Normal and Pathological Cytology and Histology, School of Medicine. University of Seville, Seville, Spain.
[31]
Department of Pathology, Institute of Biomedicine of Sevilla (IBiS), Virgen del Rocio University Hospital, CSIC/University of Sevilla/CIBERONC, Seville, Spain.
[32]
Department of Pathological Anatomy, Clínica Universidad de Navarra, University of Navarra, Pamplona, Spain.
[33]
Department of Pathology and Laboratory Medicine, KK Women's and Children's Hospital, Singapore, Republic of Singapore.
[34]
Department of Neurosurgery, National Neuroscience Institute, Singapore, Republic of Singapore.
[35]
National Center of Pathology (NCP), Laboratoire National de Santé (LNS), Dudelange, Luxembourg.
[36]
National Center of Pathology (NCP), Laboratoire National de Santé (LNS), Dudelange, Luxembourg.;Luxembourg Center of Neuropathology (LCNP), Luxembourg, Luxembourg.;Luxembourg Centre for Systems Biomedicine (LCSB), University of Luxembourg, Luxembourg, Luxembourg.;Department of Oncology (DONC), Luxembourg Institute of Health (LIH), Luxembourg, Luxembourg.
[37]
Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[38]
Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.;Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.;Research Institute Children's Cancer Center Hamburg, Hamburg, Germany.
[39]
Department of Neurology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
[40]
Department of Neuropathology, Institute of Pathology and Neuropathology, University Hospital of Tübingen, Tübingen, Germany.
[41]
Department of Pathology, New York University School of Medicine, New York, NY, USA.
[42]
Institute of Pathology, Cologne University Hospital, Cologne, Germany.
[43]
Department of Pediatric Hematology and Oncology, University Children's Hospital, Frankfurt/Main, Germany.
[44]
Institute of Pathology, Sozialstiftung Bamberg, Klinikum am Bruderwald, Bamberg, Germany.
[45]
Theodor-Boveri-Institute/Biocenter, Developmental Biochemistry, Würzburg University, Würzburg, Germany.
[46]
Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.;Department of Pathology, Amsterdam University Medical Centers/VUmc, Amsterdam, The Netherlands.
[47]
Department of Pathology, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.
[48]
Department of Neurodegeneration, Institute of Neurology, University College London, London, UK.;Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.
[49]
Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK.;Department of Molecular Neuroscience, UCL Queen Square Institute of Neurology, University College London, London, UK.
[50]
Research Department of Pathology, University College London, London, UK.
[51]
Division of Applied Bioinformatics, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
[52]
Translational and Functional Cancer Genomics, National Center for Tumor Diseases (NCT) and German Cancer Research Center (DKFZ), Heidelberg, Germany.;Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Dresden, Germany.;Center for Personalized Oncology, National Center for Tumor Diseases (NCT) Dresden and University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany.;German Cancer Consortium (DKTK), Dresden, Germany.
[53]
Department of Translational Medical Oncology, National Center for Tumor Diseases (NCT) Dresden and German Cancer Research Center (DKFZ), Dresden, Germany.;Center for Personalized Oncology, National Center for Tumor Diseases (NCT) Dresden and University Hospital Carl Gustav Carus Dresden at TU Dresden, Dresden, Germany.;German Cancer Consortium (DKTK), Dresden, Germany.
[54]
Sarcoma Research Group, Oncobell Program, Bellvitge Biomedical Research Institute (IDIBELL), CIBERONC, Barcelona, Catalonia, Spain.
[55]
Department of Pediatric Onco-Hematology and Developmental Tumor Biology Laboratory, Hospital Sant Joan de Déu, Barcelona, Catalonia, Spain.
[56]
Pediatric Solid Tumor Laboratory, Human Genetic Department, Research Institute of Rare Diseases, Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
[57]
Medical Oncology Service, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), University of Barcelona, Barcelona, Catalonia, Spain.
[58]
Cancer Epigenetics and Biology Program (PEBC), Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Catalonia, Spain.
[59]
Josep Carreras Leukaemia Research Institute (IJC), Badalona, Barcelona, Catalonia, Spain.;Centro de Investigacion Biomedica en Red Cancer (CIBERONC), Madrid, Spain.;Institucio Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Catalonia, Spain.;Physiological Sciences Department, School of Medicine and Health Sciences, University of Barcelona (UB), Barcelona, Catalonia, Spain.
[60]
Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
[61]
Gerhard Domagk Institute of Pathology, University Hospital Münster, Münster, Germany.
[62]
Department of Histopathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, Middlesex, UK.;University College London Cancer Institute, London, UK.
[63]
Pediatrics III Pediatric Hematology, Oncology, Immunology, Cardiology, Pulmonology, West German Cancer Center, University Hospital Essen, Essen, Germany.;International Ewing Sarcoma Study Group, German Cancer Consortium (DKTK), West German Cancer Center (WTZ), University Duisburg-Essen, Essen, Germany.
[64]
Division of Surgical Oncology and Thoracic Surgery, Mannheim University Medical Center, University of Heidelberg, Mannheim, Germany.
[65]
Bone Tumour Reference Centre at the Institute of Pathology, University Hospital Basel and University of Basel, Basel, Switzerland.
[66]
Division of Translational Pathology, Gerhard Domagk Institute of Pathology, University Hospital Münster, Münster, Germany.
[67]
Department of Pediatric Pathology, University Hospital of Schleswig-Holstein, Kiel, Germany.
[68]
Department of Pathology, Radboud University Medical Center, Nijmegen, The Netherlands.
[69]
Institute of Pathology, SRH Poliklinik Gera GmbH, Gera, Germany.;Institute of Pathology, Jena University Hospital, Jena, Germany.
[70]
Department of Neuropathology, Charité Universitätsmedizin Berlin, Berlin, Germany.
[71]
Department of Neuropathology, Institute of Pathology, Heidelberg University Hospital, Heidelberg, Germany. andreas.vondeimling@med.uni-heidelberg.de.;Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. andreas.vondeimling@med.uni-heidelberg.de.
[72]
医学主题词
算法(Algorithms);骨肿瘤(Bone Neoplasms);队列研究(Cohort Studies);DNA拷贝数变异(DNA Copy Number Variations);DNA甲基化(DNA Methylation);人类(Humans);因特网(Internet);结果可重复性(Reproducibility of Results);肉瘤(Sarcoma);敏感性与特异性(Sensitivity and Specificity);软组织肿瘤(Soft Tissue Neoplasms)
DOI
10.1038/s41467-020-20603-4
PMID
33479225
发布时间
2022-07-16
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Nature communications
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