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首页> Journal of ethnopharmacology> Prediction of the therapeutic mechanism responsible for the effects of Sophora japonica flower buds on contact dermatitis by network-based pharmacological analysis.

Prediction of the therapeutic mechanism responsible for the effects of Sophora japonica flower buds on contact dermatitis by network-based pharmacological analysis.

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作者： Younsook,Kim ^[1] ; Yoona,Oh ^[2] ; Hongbum,Lee ^[2] ; Beodeul,Yang ^[2] ; Chan-Hun,Choi ^[3] ; Hyunwoo,Jeong ^[4] ; Hyungwoo,Kim ^[5] ; Wongun,An ^[2]

作者单位： Gene & Cell Therapy Research Center for Vessel-associated Diseases, Pusan National University, Yangsan, Gyeongnam, 50612, South Korea. ^[1] Division of Pharmacology, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, 50612, South Korea. ^[2] Department of Physiology, College of Korean Medicine, Dongshin University, South Korea. ^[3] Department of Pathology, College of Korean Medicine, Dongshin University, Naju, Jeonnam, 58245, South Korea. ^[4] Division of Pharmacology, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, 50612, South Korea. Electronic address: kronos7@pusan.ac.kr. ^[5]

关键词 Contact dermatitis Dermatosis Inflammation Network-based systems pharmacological analysis Sophora japonica Traditional medicine

主题词动物(Animals);环氧化酶2(Cyclooxygenase 2);细胞因子类(Cytokines);数据库, 事实型(Databases, Factual);皮炎, 接触性(Dermatitis, Contact);二硝基氟苯(Dinitrofluorobenzene);疾病模型, 动物(Disease Models, Animal);中草药(Drugs, Chinese Herbal);花(Flowers);基因表达调控(Gene Expression Regulation);增生(Hyperplasia);炎症(Inflammation);角化病(Keratosis);男(雄)性(Male);代谢网络和途径(Metabolic Networks and Pathways);小鼠, 近交BALB C(Mice, Inbred BALB C);槐属(Sophora);小鼠(Mice)

DOI 10.1016/j.jep.2021.113843

PMID 33493588

发布时间 2024-02-26

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Journal of ethnopharmacology

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