SIRT7-dependent deacetylation of NPM promotes p53 stabilization following UV-induced genotoxic stress.

导出 OA

翻译打印收藏纠错

作者： Alessandro,Ianni ^[1] ; Poonam,Kumari ^[2] ; Shahriar,Tarighi ^[2] ; Nicolas G,Simonet ^[3] ; Daniela,Popescu ^[2] ; Stefan,Guenther ^[2] ; Soraya,Hölper ^[2] ; Andreas,Schmidt ^[4] ; Christian,Smolka ^[2] ; Shijing,Yue ^[5] ; Marcus,Krüger ^[6] ; Claudia,Fiorillo ^[4] ; Alejandro,Vaquero ^[7] ; Eva,Bober ^[3] ; Thomas,Braun ^[2]

作者单位： Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany; alessandro.ianni@mpi-bn.mpg.de thomas.braun@mpi-bn.mpg.de. ^[1] Department of Cardiac Development and Remodeling, Max Planck Institute for Heart and Lung Research, 61231 Bad Nauheim, Germany. ^[2] Chromatin Biology Laboratory, Josep Carreras Leukaemia Research Institute (IJC), 08916 Barcelona, Spain. ^[3] Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Universität zu Köln, 50931 Köln, Germany. ^[4] Medizin III Kardiologie und Angiologie, Universitätsklinikum Freiburg, 79106 Freiburg, Germany. ^[5] The State International Science & Technology Cooperation Base of Tumor Immunology and Biological Vaccines, Nankai University, Tianjin 300071, China. ^[6] Department of Experimental and Clinical Biomedical Sciences "Mario Serio," University of Firenze, Firenze 50139, Italy. ^[7] German Center for Lung Research (DZL), 35392 Giessen, Germany. ^[8] Cardiopulmonary Institute, 61231 Bad Nauheim, Germany. ^[9]

关键词 acetylation nucleolus nucleophosmin p53 sirtuins