A live attenuated-vaccine model confers cross-protective immunity against different species of the Leptospira genus.

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第一作者： Elsio A,Wunder

第一单位： Department of Epidemiology of Microbial Diseases; Yale School of Public Health, New Haven, United States.

作者： Elsio A,Wunder ^[1] ; Haritha,Adhikarla ^[2] ; Camila,Hamond ^[1] ; Katharine A,Owers Bonner ^[1] ; Li,Liang ^[1] ; Camila B,Rodrigues ^[3] ; Vimla,Bisht ^[3] ; Jarlath E,Nally ^[4] ; David P,Alt ^[1] ; Mitermayer G,Reis ^[5] ; Peter J,Diggle ^[5] ; Philip L,Felgner ^[2] ; Albert,Ko ^[6]

作者单位： Department of Epidemiology of Microbial Diseases; Yale School of Public Health, New Haven, United States. ^[1] Gonçalo Moniz Institute, Oswaldo Cruz Foundation; Brazilian Ministry of Health, Salvador, Brazil. ^[2] Department of Medicine, Division of Infectious Disease; University of California Irvine, Irvine, United States. ^[3] Institute of Technology in Immunobiology, Oswaldo Cruz Foundation; Brazilian Ministry of Health, Rio de Janeiro, Brazil. ^[4] Infectious Bacterial Diseases Research Unit, National Animal Disease Center, Agricultural Research Service; United States Department of Agriculture, Ames, United States. ^[5] CHICAS, Lancaster Medical School; Lancaster University, Lancaster, United Kingdom. ^[6]

关键词 cross-protective immunity infectious disease leptospira leptospirosis live attenuated vaccine microbiology