p21<sup>WAF1/CIP1</sup> promotes p53 protein degradation by facilitating p53-Wip1 and p53-Mdm2 interaction.

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作者： Jihyun,Lee ^[1] ; Jongdoo,Kim ^[1] ; Eun Mi,Kim ^[1] ; Ukjin,Kim ^[1] ; A-Ram,Kang ^[1] ; Jong Kuk,Park ^[1] ; Hong-Duck,Um ^[2]

作者单位： Division of Radiation Biomedical Research, Korea Institute of Radiological & Medical Sciences, Seoul, South Korea. ^[1] Division of Radiation Biomedical Research, Korea Institute of Radiological & Medical Sciences, Seoul, South Korea. Electronic address: hdum@kirams.re.kr. ^[2]

关键词 Mdm2 Tumor suppression Wip1 p21 p53

主题词细胞系, 肿瘤(Cell Line, Tumor);周期素依赖激酶抑制剂p21(Cyclin-Dependent Kinase Inhibitor p21);人类(Humans);肿瘤(Neoplasms);磷酰化(Phosphorylation);蛋白质相互作用域和基序(Protein Interaction Domains and Motifs);原癌基因蛋白质c-mdm2(Proto-Oncogene Proteins c-mdm2);信号传导(Signal Transduction);肿瘤抑制蛋白质p53(Tumor Suppressor Protein p53)

DOI 10.1016/j.bbrc.2021.01.074

PMID 33503543

发布时间 2021-08-31

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Biochemical and biophysical research communications

2021年543卷

23-28页

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p21<sup>WAF1/CIP1</sup> promotes p53 protein degradation by facilitating p53-Wip1 and p53-Mdm2 interaction.

Biochemical and biophysical research communications

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Biochemical and biophysical research communications

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p21<sup>WAF1/CIP1</sup> promotes p53 protein degradation by facilitating p53-Wip1 and p53-Mdm2 interaction.

Biochemical and biophysical research communications

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Biochemical and biophysical research communications

相关期刊

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