Epidermal growth factor receptor tyrosine kinase inhibitor remodels tumor microenvironment by upregulating LAG-3 in advanced non-small-cell lung cancer.

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第一作者： Juan,Zhou

第一单位： Department of Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China.

作者： Juan,Zhou ^[1] ; Xin,Yu ^[1] ; Likun,Hou ^[2] ; Jing,Zhao ^[1] ; Fei,Zhou ^[1] ; Xiangling,Chu ^[1] ; Yan,Wu ^[1] ; Caicun,Zhou ^[1] ; Chunxia,Su ^[3]

作者单位： Department of Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China. ^[1] Department of Pathology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China. ^[2] Department of Oncology, Shanghai Pulmonary Hospital & Thoracic Cancer Institute, Tongji University School of Medicine, Shanghai, China. Electronic address: susu_mail@126.com. ^[3]

关键词 EGFR-TKI Immune checkpoint proteins LAG-3 NSCLC Tumor immune microenvironment

主题词癌, 非小细胞肺(Carcinoma, Non-Small-Cell Lung);人类(Humans);肺肿瘤(Lung Neoplasms);突变(Mutation);蛋白激酶抑制剂(Protein Kinase Inhibitors);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/j.lungcan.2021.01.010

PMID 33508527

发布时间 2021-06-21

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