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3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer.

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第一作者: Barrie,Peck
第一单位: The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom.;Division of Molecular Pathology, The Institute of Cancer Research, London, England, United Kingdom.
作者单位: The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom.;Division of Molecular Pathology, The Institute of Cancer Research, London, England, United Kingdom. [1] The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom. [2] The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom.;Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom. [3] The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom.;Division of Stem Cells and Cancer, The Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia. [4] Division of Cancer Biology, The Institute of Cancer Research, London, England, United Kingdom. [5] Faculty of Life Sciences, University of Manchester, Manchester, England, United Kingdom. [6] SGC Oxford, University of Oxford, Oxford, England, United Kingdom. [7] The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom.;Breast Cancer Now Research Unit, King's College London, London, England, United Kingdom. [8] The Royal Marsden NHS Foundation Trust, London, England, United Kingdom. [9] Department of Medical Oncology, The Institute of Oncology and Radiology of Serbia, Belgrade, Serbia. [10] Department of Pathology and Cytology, The Institute of Oncology and Radiology of Serbia, Belgrade, Serbia. [11] Clinical Trials and Statistics Unit, The Institute of Cancer Research, London, England, United Kingdom. [12] Department of Drug Development (DITEP), Gustave Roussy Cancer Campus, Université Paris-Saclay, Villejuif, France.;UMR981, ATIP-Avenir team, INSERM, Villejuif, France. [13] Centre for Cancer Research and Cell Biology, Queen's University Belfast, Belfast, Northern Ireland, United Kingdom. [14] Division of Molecular Pathology, The Institute of Cancer Research, London, England, United Kingdom. [15] The Breast Cancer Now Toby Robins Research Centre, The Institute of Cancer Research, London, England, United Kingdom. rachael.natrajan@icr.ac.uk.;Division of Molecular Pathology, The Institute of Cancer Research, London, England, United Kingdom. [16]
DOI 10.1158/0008-5472.CAN-20-1822
PMID 33509944
发布时间 2025-05-30
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