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Nintedanib targets KIT D816V neoplastic cells derived from induced pluripotent stem cells of systemic mastocytosis.

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第一作者: Marcelo A S,Toledo
第一单位: Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.;Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.;Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University Medical School, Aachen, Germany.
作者单位: Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.;Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany.;Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University Medical School, Aachen, Germany. [1] Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.;Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University, Aachen, Germany. [2] Division of Hematology and Hemostaseology, Department of Internal Medicine I, and.;Ludwig Boltzmann Institute for Hematology and Oncology, Medical University of Vienna, Vienna, Austria. [3] Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University Medical School, Aachen, Germany. [4] Institute of Neuroscience and Medicine, Institute for Advanced Simulation, Jülich, Germany. [5] Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University Medical School, Aachen, Germany.;Institute of Neuroscience and Medicine, Institute for Advanced Simulation, Jülich, Germany.;Jülich Supercomputing Centre, Research Centre Jülich, Jülich, Germany. [6] Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.;iCAN Digital Precision Cancer Medicine Flagship, Helsinki, Finland. [7] Hematology Research Unit Helsinki, Helsinki University Hospital Comprehensive Cancer Center, Helsinki, Finland.;Translational Immunology Research Program and Department of Clinical Chemistry and Hematology, University of Helsinki, Helsinki, Finland. [8] Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University Medical School, Aachen, Germany.;Institute of Pathology and. [9] Institute for Human Genetics, RWTH Aachen University Hospital, Aachen, Germany. [10] Institute for Biomedical Engineering, Department of Cell Biology, RWTH Aachen University Medical School, Aachen, Germany.;Helmholtz-Institute for Biomedical Engineering, Stem Cell Biology and Cellular Engineering, RWTH Aachen University Medical School, Aachen, Germany. [11] Institute of Pathology and. [12] Department of Hematology and Oncology, University Medical Centre Mannheim, Heidelberg University, Mannheim, Germany; and. [13] Department of Pharmacology, Boehringer Ingelheim RCV, Vienna, Austria. [14]
DOI 10.1182/blood.2019004509
PMID 33512435
发布时间 2021-12-14
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Blood

Blood

2021年137卷15期

2070-2084页

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