首页> The Journal of clinical investigation> RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.

RNF168 regulates R-loop resolution and genomic stability in BRCA1/2-deficient tumors.

导出 OA

翻译打印收藏纠错

第一作者： Parasvi S,Patel

第一单位： Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.

作者： Parasvi S,Patel ^[1] ; Karan Joshua,Abraham ^[2] ; Kiran Kumar Naidu,Guturi ^[1] ; Marie-Jo,Halaby ^[1] ; Zahra,Khan ^[1] ; Luis,Palomero ^[3] ; Brandon,Ho ^[4] ; Shili,Duan ^[1] ; Jonathan,St-Germain ^[1] ; Arash,Algouneh ^[2] ; Francesca,Mateo ^[3] ; Samah,El Ghamrasni ^[1] ; Haithem,Barbour ^[5] ; Daniel R,Barnes ^[6] ; Jonathan,Beesley ^[7] ; Otto,Sanchez ^[8] ; Hal K,Berman ^[9] ; Grant W,Brown ^[4] ; El Bachir,Affar ^[5] ; Georgia,Chenevix-Trench ^[7] ; Antonis C,Antoniou ^[6] ; Cheryl H,Arrowsmith ^[1] ; Brian,Raught ^[1] ; Miquel Angel,Pujana ^[3] ; Karim,Mekhail ^[2] ; Anne,Hakem ^[1] ; Razqallah,Hakem ^[10]

作者单位： Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and. ^[1] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. ^[2] Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat, Barcelona, Catalonia, Spain. ^[3] Department of Biochemistry and Donnelly Centre, University of Toronto, Toronto, Ontario, Canada. ^[4] Centre de Recherche, Hôpital Maisonneuve-Rosemont, Montreal, Quebec, Canada. ^[5] Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom. ^[6] Cancer Division, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia. ^[7] University of Ontario Institute of Technology, Oshawa, Ontario, Canada. ^[8] Toronto General Research Institute, Toronto, Ontario, Canada. ^[9] Princess Margaret Cancer Centre, University Health Network and Department of Medical Biophysics, and.;Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada. ^[10]

关键词 Breast cancer Cell Biology Molecular genetics Mouse models Oncology