Dangerous Stops: Nonsense Mutations Can Dramatically Increase Frequency of Prion Conversion.

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第一作者： Alexander A,Dergalev

第一单位： A.N. Bach Institute of Biochemistry, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 119071 Moscow, Russia.

作者： Alexander A,Dergalev ^[1] ; Valery N,Urakov ^[1] ; Michael O,Agaphonov ^[1] ; Alexander I,Alexandrov ^[1] ; Vitaly V,Kushnirov ^[1]

作者单位： A.N. Bach Institute of Biochemistry, Federal Research Center "Fundamentals of Biotechnology" of the Russian Academy of Sciences, 119071 Moscow, Russia. ^[1]

关键词 Rnq1 Sup35 amyloid prion prion appearance prion structure proteinase

主题词淀粉样蛋白(Amyloid);淀粉样变性(Amyloidosis);密码子, 无义(Codon, Nonsense);真菌蛋白质类(Fungal Proteins);质谱分析法(Mass Spectrometry);朊病毒(Prions);RNA剪接(RNA Splicing)

DOI 10.3390/ijms22041542

PMID 33546497

发布时间 2021-04-19

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准确一般字义偏差语意偏离译文作用小提交