Use of Synonymous Deoptimization to Derive Modified Live Attenuated Strains of Foot and Mouth Disease Virus.

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第一作者： Fayna,Diaz-San Segundo

第一单位： Plum Island Animal Disease Center (PIADC), Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States.

作者： Fayna,Diaz-San Segundo ^[1] ; Gisselle N,Medina ^[1] ; Edward,Spinard ^[2] ; Anna,Kloc ^[1] ; Elizabeth,Ramirez-Medina ^[3] ; Paul,Azzinaro ^[1] ; Steffen,Mueller ^[3] ; Elizabeth,Rieder ^[1] ; Teresa,de Los Santos ^[4]

作者单位： Plum Island Animal Disease Center (PIADC), Agricultural Research Service, United States Department of Agriculture, Greenport, NY, United States. ^[1] Kansas State University College of Veterinary Medicine, Manhattan, KS, United States. ^[2] PIADC Research Participation Program, Oak Ridge Institute for Science and Education, Oak Ridge, TN, United States. ^[3] Department of Pathobiology and Veterinary Science, University of Connecticut, Storrs, CT, United States. ^[4] Codagenix, Inc., Farmingdale, NY, United States. ^[5]

关键词 FMD FMDV attenuation codon bias synonymous deoptimization vaccine

DOI 10.3389/fmicb.2020.610286

PMID 33552021

发布时间 2021-02-10

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Frontiers in microbiology

2020年11卷

610286页

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Use of Synonymous Deoptimization to Derive Modified Live Attenuated Strains of Foot and Mouth Disease Virus.

Frontiers in microbiology

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Frontiers in microbiology

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Use of Synonymous Deoptimization to Derive Modified Live Attenuated Strains of Foot and Mouth Disease Virus.

Frontiers in microbiology

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Frontiers in microbiology

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