Homeodomain protein Six4 prevents the generation of supernumerary Drosophila type II neuroblasts and premature differentiation of intermediate neural progenitors.
第一作者:
Rui,Chen
第一单位:
Department of Neuroscience and Physiology, State University of New York Upstate Medical University, Syracuse, New York, United States of America.
作者:
医学主题词
动物(Animals);动物, 基因修饰(Animals, Genetically Modified);脑(Brain);细胞计数(Cell Count);细胞去分化(Cell Dedifferentiation);细胞分化(Cell Differentiation);细胞系(Cell Line);细胞谱系(Cell Lineage);DNA结合蛋白质类(DNA-Binding Proteins);果蝇蛋白质类(Drosophila Proteins);黑腹果蝇(Drosophila melanogaster);基因表达调控, 发育期(Gene Expression Regulation, Developmental);同源盒结构域蛋白质类(Homeodomain Proteins);显微镜检查, 共焦(Microscopy, Confocal);神经组织蛋白质类(Nerve Tissue Proteins);神经干细胞(Neural Stem Cells);神经元(Neurons);蛋白质结合(Protein Binding);原癌基因蛋白质类(Proto-Oncogene Proteins);RNA干扰(RNA Interference);转录因子(Transcription Factors)
DOI
10.1371/journal.pgen.1009371
PMID
33556050
发布时间
2021-06-21
基金项目
R01 NS085232/NS/NINDS NIH HHS/United States
R21 NS109748/NS/NINDS NIH HHS/United States
- 浏览1
PLoS genetics
e1009371页
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