首页> STAR protocols> <i>Ex vivo</i> assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells.

<i>Ex vivo</i> assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells.

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第一作者： Katrin Anne,Becker

第一单位： Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.

作者： Katrin Anne,Becker ^[1] ; Alexander,Carpinteiro ^[2] ; Markus,Hoffmann ^[3] ; Stefan,Pöhlmann ^[3] ; Johannes,Kornhuber ^[4] ; Erich,Gulbins ^[5]

作者单位： Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany. ^[1] Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.;Department of Hematology, University Hospital Essen, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany. ^[2] Infection Biology Unit, German Primate Center - Leibniz Institute for Primate Research, Göttingen, Germany.;Faculty of Biology and Psychology, University of Göttingen, 37073 Göttingen, Germany. ^[3] Department of Psychiatry and Psychotherapy, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Schwabachanlage 6, 91054 Erlangen, Germany. ^[4] Institute of Molecular Biology, University of Duisburg-Essen, Hufelandstrasse 55, 45122 Essen, Germany.;Department of Surgery, University of Cincinnati Medical School, 231 Albert Sabin Way, ML0558, Cincinnati, OH 45267, USA. ^[5]

关键词 Cell isolation Cell-based assays

主题词抗病毒药(Antiviral Agents);细胞培养技术(Cell Culture Techniques);细胞, 培养的(Cells, Cultured);药物评价, 临床前(Drug Evaluation, Preclinical);上皮细胞(Epithelial Cells);人类(Humans);鼻黏膜(Nasal Mucosa);鞘脂类(Sphingolipids);水疱性口炎印第安纳病毒(Vesicular stomatitis Indiana virus)

DOI 10.1016/j.xpro.2021.100356

PMID 33558862

发布时间 2022-02-17

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<i>Ex vivo</i> assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells.

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<i>Ex vivo</i> assay to evaluate the efficacy of drugs targeting sphingolipids in preventing SARS-CoV-2 infection of nasal epithelial cells.

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STAR protocols

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