首页> Pharmaceutical research> Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [<sup>11</sup>C]Metoclopramide in Mice.

Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [<sup>11</sup>C]Metoclopramide in Mice.

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第一作者： Irene,Hernández-Lozano

第一单位： Department of Clinical Pharmacology, Medical University of Vienna, A-1090, Vienna, Austria.

作者： Irene,Hernández-Lozano ^[1] ; Severin,Mairinger ^[2] ; Michael,Sauberer ^[2] ; Johann,Stanek ^[2] ; Thomas,Filip ^[2] ; Thomas,Wanek ^[2] ; Giuliano,Ciarimboli ^[3] ; Nicolas,Tournier ^[4] ; Oliver,Langer ^[5]

作者单位： Department of Clinical Pharmacology, Medical University of Vienna, A-1090, Vienna, Austria. ^[1] Preclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria. ^[2] Medicine Clinic D. Experimental Nephrology, University Hospital Münster, Münster, Germany. ^[3] Laboratoire d'Imagerie Biomédicale Multimodale (BioMaps), CEA, CNRS, Inserm, Service Hospitalier Frédéric Joliot, Université Paris-Saclay, Orsay, France. ^[4] Department of Clinical Pharmacology, Medical University of Vienna, A-1090, Vienna, Austria. oliver.langer@meduniwien.ac.at.;Preclinical Molecular Imaging, AIT Austrian Institute of Technology GmbH, Seibersdorf, Austria. oliver.langer@meduniwien.ac.at.;Department of Biomedical Imaging and Image-guided Therapy, Division of Nuclear Medicine, Medical University of Vienna, Vienna, Austria. oliver.langer@meduniwien.ac.at. ^[5]

关键词 CYP2D6 [11C]metoclopramide multidrug and toxin extrusion proteins (MATEs)organic cation transporters (OCTs)positron emission tomography (PET)