Myeloid malignancies with 5q and 7q deletions are associated with extreme genomic complexity, biallelic TP53 variants, and very poor prognosis.

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第一作者： Beth A,Pitel

第一单位： Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic, Rochester, MN, USA.

作者： Beth A,Pitel ^[1] ; Neeraj,Sharma ^[1] ; Cinthya,Zepeda-Mendoza ^[1] ; James B,Smadbeck ^[2] ; Kathryn E,Pearce ^[3] ; Joselle M,Cook ^[1] ; George,Vasmatzis ^[4] ; Zohar,Sachs ^[3] ; Rashmi,Kanagal-Shamanna ^[5] ; David,Viswanatha ^[6] ; Sheng,Xiao ^[7] ; Robert B,Jenkins ^[8] ; Xinjie,Xu ^[1] ; Nicole L,Hoppman ^[1] ; Rhett P,Ketterling ^[1] ; Jess F,Peterson ^[1] ; Patricia T,Greipp ^[1] ; Linda B,Baughn ^[1]

作者单位： Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic, Rochester, MN, USA. ^[1] Cytogenetics and Genomic Microarray Laboratory, ARUP Laboratories, Salt Lake City, UT, USA. ^[2] Center for Individualized Medicine-Biomarker Discovery, Mayo Clinic, Rochester, MN, USA. ^[3] Department of Medicine, Division of Hematology, Mayo Clinic, Rochester, MN, USA. ^[4] Division of Hematology, Oncology, and Transplantation, Department of Medicine and Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA. ^[5] Department of Hematopathology, University of Texas MD Anderson Cancer Center, Houston, TX, USA. ^[6] Department of Laboratory Medicine and Pathology, Division of Hematopathology, Mayo Clinic, Rochester, MN, USA. ^[7] Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. ^[8] Department of Laboratory Medicine and Pathology, Division of Laboratory Genetics and Genomics, Mayo Clinic, Rochester, MN, USA. baughn.linda@mayo.edu. ^[9]