Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors.

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作者： Ethel J,Ngen ^[1] ; Ying,Chen ^[1] ; Babak Behnam,Azad ^[1] ; Srikanth,Boinapally ^[1] ; Desmond,Jacob ^[1] ; Ala,Lisok ^[1] ; Chentian,Shen ^[1] ; Mir S,Hossain ^[1] ; Jiefu,Jin ^[1] ; Zaver M,Bhujwalla ^[1] ; Martin G,Pomper ^[2] ; Sangeeta R,Banerjee ^[1]

作者单位： The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA. ^[1] The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA. ^[2] The F. M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Research Institute, Baltimore, Maryland 21205, USA. ^[3]

关键词 enhanced permeability and retention (EPR) effect magnetic nanoparticle delivery magnetic resonance imaging (MRI)photodynamic therapy (PDT)prostate cancer

主题词动物(Animals);抗原, 表面(Antigens, Surface);细胞系, 肿瘤(Cell Line, Tumor);谷氨酸羧肽酶Ⅱ(Glutamate Carboxypeptidase II);人类(Humans);磁共振成像(Magnetic Resonance Imaging);磁性纳米粒子(Magnetite Nanoparticles);男(雄)性(Male);小鼠(Mice);光化学疗法(Photochemotherapy);光敏感药(Photosensitizing Agents);前列腺肿瘤(Prostatic Neoplasms);异种移植模型抗肿瘤试验(Xenograft Model Antitumor Assays)

DOI 10.7150/ntno.52361

PMID 33564617

发布时间 2021-06-01

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Nanotheranostics

2021年5卷2期

182-196页

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Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors.

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Prostate-specific membrane antigen (PSMA)-targeted photodynamic therapy enhances the delivery of PSMA-targeted magnetic nanoparticles to PSMA-expressing prostate tumors.

Nanotheranostics

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Nanotheranostics

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