Sensitivity of Osteosarcoma Cells to Concentration-Dependent Bioactivities of Lipid Peroxidation Product 4-Hydroxynonenal Depend on Their Level of Differentiation.

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第一作者： Suzana Borovic,Sunjic

第一单位： Laboratory for Oxidative Stress (LabOS), Division of Molecular Medicine, Rudjer Boskovic Institute, HR-10000 Zagreb, Croatia.

作者： Suzana Borovic,Sunjic ^[1] ; Ana Cipak,Gasparovic ^[1] ; Morana,Jaganjac ^[1] ; Gerald,Rechberger ^[2] ; Andreas,Meinitzer ^[3] ; Tilman,Grune ^[4] ; Sepp D,Kohlwein ^[2] ; Branka,Mihaljevic ^[1] ; Neven,Zarkovic ^[1]

作者单位： Laboratory for Oxidative Stress (LabOS), Division of Molecular Medicine, Rudjer Boskovic Institute, HR-10000 Zagreb, Croatia. ^[1] Institute of Molecular Biosciences, Bio TechMed-Graz, University of Graz, 8010 Graz, Austria. ^[2] University Clinic of Traumatology, University of Graz, 8010 Graz, Austria. ^[3] Department of Molecular Toxicology, German Institute of Human Nutrition Potsdam-Rehbruecke, 14558 Nuthetal, Germany.;Department of Physiological Chemistry, Faculty of Chemistry, University of Vienna, A-1090 Vienna, Austria. ^[4]

关键词 4-hydroxynonenal ALP C20:3 GSH GST HNE-protein adducts apoptosis differentiation fatty acid human osteosarcoma proliferation proteasomal activity

主题词醛类(Aldehydes);碱性磷酸酶(Alkaline Phosphatase);细胞凋亡(Apoptosis);细胞分化(Cell Differentiation);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);谷胱甘肽(Glutathione);谷胱甘肽转移酶(Glutathione Transferase);人类(Humans);脂质过氧化作用(Lipid Peroxidation);坏死(Necrosis);骨肉瘤(Osteosarcoma);蛋白酶体内肽酶复合物(Proteasome Endopeptidase Complex)

DOI 10.3390/cells10020269

PMID 33572933

发布时间 2021-10-15

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2021年10卷2期

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Sensitivity of Osteosarcoma Cells to Concentration-Dependent Bioactivities of Lipid Peroxidation Product 4-Hydroxynonenal Depend on Their Level of Differentiation.

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Sensitivity of Osteosarcoma Cells to Concentration-Dependent Bioactivities of Lipid Peroxidation Product 4-Hydroxynonenal Depend on Their Level of Differentiation.

Cells

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Cells

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