Molecular principles of Piwi-mediated cotranscriptional silencing through the dimeric SFiNX complex.

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第一作者： Jakob,Schnabl

第一单位： Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.;Vienna BioCenter PhD Program, Doctoral School at the University of Vienna and Medical University of Vienna, 1030 Vienna, Austria.

作者： Jakob,Schnabl ^[1] ; Juncheng,Wang ^[2] ; Ulrich,Hohmann ^[3] ; Maja,Gehre ^[4] ; Julia,Batki ^[4] ; Veselin I,Andreev ^[1] ; Kim,Purkhauser ^[4] ; Nina,Fasching ^[4] ; Peter,Duchek ^[4] ; Maria,Novatchkova ^[4] ; Karl,Mechtler ^[5] ; Clemens,Plaschka ^[5] ; Dinshaw J,Patel ^[2] ; Julius,Brennecke ^[4]

作者单位： Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.;Vienna BioCenter PhD Program, Doctoral School at the University of Vienna and Medical University of Vienna, 1030 Vienna, Austria. ^[1] Structural Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10065, USA. ^[2] Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria.;Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), 1030 Vienna, Austria. ^[3] Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna BioCenter (VBC), 1030 Vienna, Austria. ^[4] Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), 1030 Vienna, Austria. ^[5]

关键词 Drosophila oogenesis LC8 Panoramix Piwi cotranscriptional silencing heterochromatin formation molecular condensates piRNA pathway transposon silencing