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首页> Pharmaceutical research> On the Use of Computational Fluid Dynamics (CFD) Modelling to Design Improved Dry Powder Inhalers.

On the Use of Computational Fluid Dynamics (CFD) Modelling to Design Improved Dry Powder Inhalers.

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作者： David F,Fletcher ^[1] ; Vishal,Chaugule ^[2] ; Larissa,Gomes Dos Reis ^[3] ; Paul M,Young ^[3] ; Daniela,Traini ^[3] ; Julio,Soria ^[4]

作者单位： School of Chemical and Biomolecular Engineering, The University of Sydney, Sydney, Australia. ^[1] Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Department of Mechanical and Aerospace Engineering, Monash University, Clayton Campus, Melbourne, Australia. vishal.chaugule@monash.edu. ^[2] Respiratory Technology, Woolcock Institute of Medical Research and Discipline of Pharmacology, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia. ^[3] Laboratory for Turbulence Research in Aerospace and Combustion (LTRAC), Department of Mechanical and Aerospace Engineering, Monash University, Clayton Campus, Melbourne, Australia. ^[4]

关键词 CFD SBES dry powder inhaler particle tracking turbulence models

主题词投药, 吸入(Administration, Inhalation);气雾剂(Aerosols);化学, 药物(Chemistry, Pharmaceutical);计算机模拟(Computer Simulation);干粉吸入器(Dry Powder Inhalers);设备设计(Equipment Design);流体动力学(Hydrodynamics);模型, 化学(Models, Chemical);粒子大小(Particle Size);粉剂(Powders);流变学(Rheology)

DOI 10.1007/s11095-020-02981-y

PMID 33575958

发布时间 2021-10-18

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Pharmaceutical research

Pharmaceutical research

2021年38卷2期

277-288页

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